Evolution of extensively drug-resistant Mycobacterium tuberculosis from a susceptible ancestor in a single patient

BACKGROUND: Mycobacterium tuberculosis is characterized by a low mutation rate and a lack of genetic recombination. Yet, the rise of extensively resistant strains paints a picture of a microbe with an impressive adaptive potential. Here we describe the first documented case of extensively drug-resis...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Genome Biol
Main Authors: Eldholm, Vegard, Norheim, Gunnstein, von der Lippe, Bent, Kinander, Wibeke, Dahle, Ulf R, Caugant, Dominique A, Mannsåker, Turid, Mengshoel, Anne Torunn, Dyrhol-Riise, Anne Ma, Balloux, Francois
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223161/
https://ncbi.nlm.nih.gov/pubmed/25418686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0490-3
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