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Evolution of extensively drug-resistant Mycobacterium tuberculosis from a susceptible ancestor in a single patient
BACKGROUND: Mycobacterium tuberculosis is characterized by a low mutation rate and a lack of genetic recombination. Yet, the rise of extensively resistant strains paints a picture of a microbe with an impressive adaptive potential. Here we describe the first documented case of extensively drug-resis...
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| Veröffentlicht in: | Genome Biol |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4223161/ https://ncbi.nlm.nih.gov/pubmed/25418686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0490-3 |
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