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Evolution of extensively drug-resistant Mycobacterium tuberculosis from a susceptible ancestor in a single patient

BACKGROUND: Mycobacterium tuberculosis is characterized by a low mutation rate and a lack of genetic recombination. Yet, the rise of extensively resistant strains paints a picture of a microbe with an impressive adaptive potential. Here we describe the first documented case of extensively drug-resis...

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Библиографические подробности
Опубликовано в: :	Genome Biol
Главные авторы:	Eldholm, Vegard, Norheim, Gunnstein, von der Lippe, Bent, Kinander, Wibeke, Dahle, Ulf R, Caugant, Dominique A, Mannsåker, Turid, Mengshoel, Anne Torunn, Dyrhol-Riise, Anne Ma, Balloux, Francois
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BioMed Central 2014
Предметы:	Research
Online-ссылка:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4223161/ https://ncbi.nlm.nih.gov/pubmed/25418686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0490-3
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Evolution of extensively drug-resistant Mycobacterium tuberculosis from a susceptible ancestor in a single patient

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