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Genome-Wide Associations between Genetic and Epigenetic Variation Influence mRNA Expression and Insulin Secretion in Human Pancreatic Islets

Genetic and epigenetic mechanisms may interact and together affect biological processes and disease development. However, most previous studies have investigated genetic and epigenetic mechanisms independently, and studies examining their interactions throughout the human genome are lacking. To iden...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Olsson, Anders H., Volkov, Petr, Bacos, Karl, Dayeh, Tasnim, Hall, Elin, Nilsson, Emma A., Ladenvall, Claes, Rönn, Tina, Ling, Charlotte
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222689/
https://ncbi.nlm.nih.gov/pubmed/25375650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004735
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