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Bim mediates apoptosis of CD127(lo) effector T cells and limits T cell memory
Following an acute T cell response, most activated effector cells die, while some survive and become memory cells. The pro-apoptotic Bcl-2 family member, Bcl-2 interacting mediator of death (Bim) is critical for eliminating most effector T cells, while expression of CD127 (IL-7Rα) has been proposed...
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| Опубликовано в: : | Eur J Immunol |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4222686/ https://ncbi.nlm.nih.gov/pubmed/16761315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200635897 |
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