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Regulation of the Interleukin-7 Receptor α Promoter by the Ets Transcription Factors PU.1 and GA-binding Protein in Developing B Cells()

Signaling through the IL-7 receptor (IL-7R) is required for development and maintenance of the immune system. The receptor for IL-7 is heterodimeric, consisting of a common γ chain (γc, encoded by Il2rg) and an α subunit (IL-7Rα, encoded by Il7r). The Il7r gene is expressed specifically in the immun...

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Publicat a:J Biol Chem
Autors principals: DeKoter, Rodney P., Schweitzer, Brock L., Kamath, Meghana B., Jones, Darrel, Tagoh, Hiromi, Bonifer, Constanze, Hildeman, David A., Huang, Kelly J.
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222673/
https://ncbi.nlm.nih.gov/pubmed/17392277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M700377200
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