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PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors.
PU.1 is a unique regulatory protein required for the generation of both the innate and the adaptive immune system. It functions exclusively in a cell-intrinsic manner to control the development of granulocytes, macrophages, and B and T lymphocytes. We demonstrate that mutation of the PU.1 gene cause...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
1998
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170777/ https://ncbi.nlm.nih.gov/pubmed/9687512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.15.4456 |
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