Myelin Basic Protein and a Multiple Sclerosis-related MBP-peptide Bind to Oligonucleotides

Aptamer ligands for myelin basic protein (MBP) were obtained using the systematic evolution of ligand by exponential enrichment (SELEX) method. Two clones were isolated from a pool of oligonucleotides and tested for MBP targeting. Using purified MBP, we demonstrated the binding activity of the aptam...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Mol Ther Nucleic Acids
Autores principales: Rozenblum, Guido Tomás, Kaufman, Tomás, Vitullo, Alfredo Daniel
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222649/
https://ncbi.nlm.nih.gov/pubmed/25202925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2014.43
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares