RPN2 Gene Confers Osteosarcoma Cell Malignant Phenotypes and Determines Clinical Prognosis

Drug resistance and metastasis are lethal characteristics of tumors. We previously demonstrated that silencing of ribophorin II (RPN2), which is part of the N-oligosaccharyl transferase complex, efficiently induced apoptosis and reduced resistance to docetaxel in human breast cancer cells. Here, we...

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Vydáno v:Mol Ther Nucleic Acids
Hlavní autoři: Fujiwara, Tomohiro, Takahashi, Ryou-u, Kosaka, Nobuyoshi, Nezu, Yutaka, Kawai, Akira, Ozaki, Toshifumi, Ochiya, Takahiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222647/
https://ncbi.nlm.nih.gov/pubmed/25181275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2014.35
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