RPN2 Gene Confers Osteosarcoma Cell Malignant Phenotypes and Determines Clinical Prognosis

Drug resistance and metastasis are lethal characteristics of tumors. We previously demonstrated that silencing of ribophorin II (RPN2), which is part of the N-oligosaccharyl transferase complex, efficiently induced apoptosis and reduced resistance to docetaxel in human breast cancer cells. Here, we...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther Nucleic Acids
Hauptverfasser: Fujiwara, Tomohiro, Takahashi, Ryou-u, Kosaka, Nobuyoshi, Nezu, Yutaka, Kawai, Akira, Ozaki, Toshifumi, Ochiya, Takahiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222647/
https://ncbi.nlm.nih.gov/pubmed/25181275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2014.35
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