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RPN2 Gene Confers Osteosarcoma Cell Malignant Phenotypes and Determines Clinical Prognosis

Drug resistance and metastasis are lethal characteristics of tumors. We previously demonstrated that silencing of ribophorin II (RPN2), which is part of the N-oligosaccharyl transferase complex, efficiently induced apoptosis and reduced resistance to docetaxel in human breast cancer cells. Here, we...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Fujiwara, Tomohiro, Takahashi, Ryou-u, Kosaka, Nobuyoshi, Nezu, Yutaka, Kawai, Akira, Ozaki, Toshifumi, Ochiya, Takahiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222647/
https://ncbi.nlm.nih.gov/pubmed/25181275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2014.35
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