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Total synthesis of the proposed structure of astakolactin

The first total synthesis of the proposed structure of astakolactin, a sesterterpene metabolite isolated from the marine sponge Cacospongia scalaris, has been achieved, mainly featuring Johnson–Claisen rearrangement, asymmetric Mukaiyama aldol reaction and MNBA-mediated lactonization.

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Beilstein J Org Chem
मुख्य लेखकों: Tonoi, Takayuki, Mameda, Keisuke, Fujishiro, Moe, Yoshinaga, Yutaka, Shiina, Isamu
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Beilstein-Institut 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222296/
https://ncbi.nlm.nih.gov/pubmed/25383112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.252
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