Myeloid expression of angiotensin converting enzyme facilitates myeloid maturation and inhibits the development of myeloid-derived suppressor cells

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells which accumulate in cancer, infection and chronic inflammation. These cells suppress T cell function and the immune response. Angiotensin converting enzyme (ACE) is a peptidase that is now known to regu...

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Publicat a:Lab Invest
Autors principals: Shen, Xiao Z., Okwan-Duodu, Derick, Blackwell, Wendell-Lamar, Ong, Frank S., Janjulia, Tea, Bernstein, Ellen A., Fuchs, Sebastien, Alkan, Serhan, Bernstein, Kenneth E.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221240/
https://ncbi.nlm.nih.gov/pubmed/24614194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2014.41
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