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Primary Ovarian Carcinomas and Abdominal Metastasis Contain 4,6-Disulfated Chondroitin Sulfate Rich Regions, Which Provide Adhesive Properties to Tumour Cells

High mortality in ovarian cancer patients is primarily caused through rapid metastasis of the tumour, but the underlying mechanisms are poorly understood. Glycosaminoglycans, are abundantly present in tumours and chondroitin sulfate-E (CSE), a highly 4,6-sulfated glycosaminoglycan, has been indicate...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Vallen, Myrtille J. E., Schmidt, Samuel, Oosterhof, Arie, Bulten, Johan, Massuger, Leon F. A. G., van Kuppevelt, Toin H.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221137/
https://ncbi.nlm.nih.gov/pubmed/25372710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111806
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