Potentially Functional SNPs (pfSNPs) as Novel Genomic Predictors of 5-FU Response in Metastatic Colorectal Cancer Patients

5-Fluorouracil (5-FU) and its pro-drug Capecitabine have been widely used in treating colorectal cancer. However, not all patients will respond to the drug, hence there is a need to develop reliable early predictive biomarkers for 5-FU response. Here, we report a novel potentially functional Single...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wang, Jingbo, Wang, Xu, Zhao, Mingjue, Choo, Su Pin, Ong, Sin Jen, Ong, Simon Y. K., Chong, Samuel S., Teo, Yik Ying, Lee, Caroline G. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221105/
https://ncbi.nlm.nih.gov/pubmed/25372392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111694
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