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Conditional transformation of a pancreatic beta-cell line derived from transgenic mice expressing a tetracycline-regulated oncogene.

Conditional oncogene expression in transgenic mice is of interest for studying the oncoprotein requirements during tumorigenesis and for deriving cell lines that can be induced to undergo growth arrest and enhance their differentiated functions. We utilized the bacterial tetracycline (Tet)-resistanc...

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Détails bibliographiques
Auteurs principaux: Efrat, S, Fusco-DeMane, D, Lemberg, H, al Emran, O, Wang, X
Format: Artigo
Langue:Inglês
Publié: 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC42210/
https://ncbi.nlm.nih.gov/pubmed/7724601
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