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Enzyme–adenylate structure of a bacterial ATP-dependent DNA ligase with a minimized DNA-binding surface

DNA ligases are a structurally diverse class of enzymes which share a common catalytic core and seal breaks in the phosphodiester backbone of double-stranded DNA via an adenylated intermediate. Here, the structure and activity of a recombinantly produced ATP-dependent DNA ligase from the bacterium P...

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Dettagli Bibliografici
Pubblicato in:Acta Crystallogr D Biol Crystallogr
Autori principali: Williamson, Adele, Rothweiler, Ulli, Schrøder Leiros, Hanna-Kirsti
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220977/
https://ncbi.nlm.nih.gov/pubmed/25372693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004714021099
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