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C10X polymorphism in the CARD8 gene is associated with bacteraemia

The NLRP3 inflammasome is an intracellular multi-protein complex that triggers caspase-1 mediated maturation of interleukin-1β (IL-1β); one of the most potent mediators of inflammation and a major cytokine produced during severe infections, like sepsis. However, the excessive cytokine levels seem to...

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Bibliografische gegevens
Gepubliceerd in:Immun Inflamm Dis
Hoofdauteurs: Asfaw Idosa, Berhane, Sahdo, Berolla, Balcha, Ermias, Kelly, Anne, Söderquist, Bo, Särndahl, Eva
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220665/
https://ncbi.nlm.nih.gov/pubmed/25400921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.14
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