Neisseria meningitidis-Induced Caspase-1 Activation in Human Innate Immune Cells Is LOS-Dependent

Meningococcal disease such as sepsis and meningitidis is hallmarked by an excessive inflammatory response. The causative agent, Neisseria meningitidis, expresses the endotoxin lipooligosaccharide (LOS) that is responsible for activation of immune cells and the release of proinflammatory cytokines. O...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Idosa, Berhane Asfaw, Kelly, Anne, Jacobsson, Susanne, Demirel, Isak, Fredlund, Hans, Särndahl, Eva, Persson, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526529/
https://ncbi.nlm.nih.gov/pubmed/31198794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6193186
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