LAMTOR2 regulates dendritic cell homeostasis through FLT3-dependent mTOR signalling

The receptor tyrosine kinase Flt3 and its ligand are crucial for dendritic cell (DC) homeostasis by activating downstream effectors including mammalian target of Rapamycin (mTOR) signalling. LAMTOR2 is a member of the Ragulator/LAMTOR complex known to regulate mTOR and extracellular signal-regulated...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Scheffler, Julia M., Sparber, Florian, Tripp, Christoph H., Herrmann, Caroline, Humenberger, Alexandra, Blitz, Johanna, Romani, Nikolaus, Stoitzner, Patrizia, Huber, Lukas A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Pub. Group 2014
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220488/
https://ncbi.nlm.nih.gov/pubmed/25336251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6138
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi