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LAMTOR2 regulates dendritic cell homeostasis through FLT3-dependent mTOR signalling
The receptor tyrosine kinase Flt3 and its ligand are crucial for dendritic cell (DC) homeostasis by activating downstream effectors including mammalian target of Rapamycin (mTOR) signalling. LAMTOR2 is a member of the Ragulator/LAMTOR complex known to regulate mTOR and extracellular signal-regulated...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Pub. Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4220488/ https://ncbi.nlm.nih.gov/pubmed/25336251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6138 |
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