Early activation of pro-fibrotic WNT5A in sepsis-induced acute lung injury

INTRODUCTION: The mechanisms of lung repair and fibrosis in the acute respiratory distress syndrome (ARDS) are poorly known. Since the role of WNT/β-catenin signaling appears to be central to lung healing and fibrosis, we hypothesized that this pathway is activated very early in the lungs after seps...

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Dettagli Bibliografici
Pubblicato in:Crit Care
Autori principali: Villar, Jesús, Cabrera-Benítez, Nuria E, Ramos-Nuez, Angela, Flores, Carlos, García-Hernández, Sonia, Valladares, Francisco, López-Aguilar, Josefina, Blanch, Lluís, Slutsky, Arthur S
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220065/
https://ncbi.nlm.nih.gov/pubmed/25331176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-014-0568-z
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