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Mechanical ventilation modulates TLR4 and IRAK-3 in a non-infectious, ventilator-induced lung injury model

BACKGROUND: Previous experimental studies have shown that injurious mechanical ventilation has a direct effect on pulmonary and systemic immune responses. How these responses are propagated or attenuated is a matter of speculation. The goal of this study was to determine the contribution of mechanic...

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Hlavní autoři: Villar, Jesús, Cabrera, Nuria E, Casula, Milena, Flores, Carlos, Valladares, Francisco, Díaz-Flores, Lucio, Muros, Mercedes, Slutsky, Arthur S, Kacmarek, Robert M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841148/
https://ncbi.nlm.nih.gov/pubmed/20199666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-27
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