Parvalbumin and GAD65 Interneuron Inhibition in the Ventral Hippocampus Induces Distinct Behavioral Deficits Relevant to Schizophrenia

Hyperactivity within the ventral hippocampus (vHPC) has been linked to both psychosis in humans and behavioral deficits in animal models of schizophrenia. A local decrease in GABA-mediated inhibition, particularly involving parvalbumin (PV)-expressing GABA neurons, has been proposed as a key mechani...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Nguyen, Robin, Morrissey, Mark D., Mahadevan, Vivek, Cajanding, Janine D., Woodin, Melanie A., Yeomans, John S., Takehara-Nishiuchi, Kaori, Kim, Jun Chul
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220027/
https://ncbi.nlm.nih.gov/pubmed/25378161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2204-14.2014
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