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GAD67 Deficiency in Parvalbumin Interneurons Produces Deficits in Inhibitory Transmission and Network Disinhibition in Mouse Prefrontal Cortex

In mammalian neocortex, the delicate balance of neural circuits is regulated by a rich repertoire of inhibitory control mechanisms mediated by diverse classes of GABAergic interneurons. A key step common to all GABAergic neurons is the synthesis of GABA, catalyzed by 2 isoforms of glutamic acid deca...

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Detalhes bibliográficos
Publicado no:Cereb Cortex
Main Authors: Lazarus, Matthew S., Krishnan, Keerthi, Huang, Z. Josh
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481616/
https://ncbi.nlm.nih.gov/pubmed/24275833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bht322
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