Foot-and-mouth disease virus leader proteinase: Structural insights into the mechanism of intermolecular cleavage

Translation of foot-and-mouth disease virus RNA initiates at one of two start codons leading to the synthesis of two forms of leader proteinase L(pro) (Lab(pro) and Lb(pro)). These forms free themselves from the viral polyprotein by intra- and intermolecular self-processing and subsequently cleave t...

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Publicado en:Virology
Main Authors: Steinberger, Jutta, Grishkovskaya, Irina, Cencic, Regina, Juliano, Luiz, Juliano, Maria A., Skern, Tim
Formato: Artigo
Idioma:Inglês
Publicado: Academic Press 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220004/
https://ncbi.nlm.nih.gov/pubmed/25240326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.08.023
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