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Foot-and-mouth disease virus leader proteinase: Structural insights into the mechanism of intermolecular cleavage

Translation of foot-and-mouth disease virus RNA initiates at one of two start codons leading to the synthesis of two forms of leader proteinase L(pro) (Lab(pro) and Lb(pro)). These forms free themselves from the viral polyprotein by intra- and intermolecular self-processing and subsequently cleave t...

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Bibliografiske detaljer
Udgivet i:Virology
Main Authors: Steinberger, Jutta, Grishkovskaya, Irina, Cencic, Regina, Juliano, Luiz, Juliano, Maria A., Skern, Tim
Format: Artigo
Sprog:Inglês
Udgivet: Academic Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220004/
https://ncbi.nlm.nih.gov/pubmed/25240326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.08.023
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