Inhibition of Kidney Proximal Tubular Glucose Reabsorption Does Not Prevent against Diabetic Nephropathy in Type 1 Diabetic eNOS Knockout Mice

BACKGROUND AND OBJECTIVE: Sodium glucose cotransporter 2 (SGLT2) is the main luminal glucose transporter in the kidney. SGLT2 inhibition results in glycosuria and improved glycaemic control. Drugs inhibiting this transporter have recently been approved for clinical use and have been suggested to hav...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Gangadharan Komala, Muralikrishna, Gross, Simon, Mudaliar, Harshini, Huang, Chunling, Pegg, Katherine, Mather, Amanda, Shen, Sylvie, Pollock, Carol A., Panchapakesan, Usha
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2014
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219667/
https://ncbi.nlm.nih.gov/pubmed/25369239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108994
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