Inhibition of Kidney Proximal Tubular Glucose Reabsorption Does Not Prevent against Diabetic Nephropathy in Type 1 Diabetic eNOS Knockout Mice

BACKGROUND AND OBJECTIVE: Sodium glucose cotransporter 2 (SGLT2) is the main luminal glucose transporter in the kidney. SGLT2 inhibition results in glycosuria and improved glycaemic control. Drugs inhibiting this transporter have recently been approved for clinical use and have been suggested to hav...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gangadharan Komala, Muralikrishna, Gross, Simon, Mudaliar, Harshini, Huang, Chunling, Pegg, Katherine, Mather, Amanda, Shen, Sylvie, Pollock, Carol A., Panchapakesan, Usha
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219667/
https://ncbi.nlm.nih.gov/pubmed/25369239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108994
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