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Restoration of structural stability and ligand binding after removal of the conserved disulfide bond in tear lipocalin
Disulfide bonds play diverse structural and functional roles in proteins. In tear lipocalin (TL), the conserved sole disulfide bond regulates stability and ligand binding. Probing protein structure often involves thiol selective labeling for which removal of the disulfide bonds may be necessary. Los...
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| Publicado no: | Biochem Biophys Res Commun |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4219327/ https://ncbi.nlm.nih.gov/pubmed/25223802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.09.029 |
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