Redox regulation of apurinic/apyrimidinic endonuclease I activity in Long-Evans Cinnamon rats during spontaneous hepatitis

The Long-Evans Cinnamon (LEC) rat is an animal model for Wilson’s disease (WD). This animal is genetically predisposed to copper accumulation in the liver, increased oxidative stress, accumulation of DNA damage, and the spontaneous development of hepatocellular carcinoma (HCC). Thus, this animal mod...

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Bibliographic Details
Published in:Mol Cell Biochem
Main Authors: Karmahapatra, Soumendra Krishna, Saha, Tapas, Adhikari, Sanjay, Woodrick, Jordan, Roy, Rabindra
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218752/
https://ncbi.nlm.nih.gov/pubmed/24337968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-013-1909-y
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