TM-07 (13)C MRS DETECTS METABOLIC FLUX ADAPTATION IN IDH MUTANT GLIOMA CELLS

The isocitrate dehydrogenase (IDH)1 mutation is associated with accumulation of 2-hydroxyglutarate (2-HG), but the metabolic fluxes associated with 2-HG production and cellular reprogramming of mutant IDH1 cells are not fully understood. The objective of this study was to use (13)C magnetic resonanc...

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Bibliografische gegevens
Gepubliceerd in:Neuro Oncol
Hoofdauteurs: Izquierdo-Garcia, Jose, Eriksson, Pia, Cai, Larry, Chaumeil, Myriam, Pieper, Russell, Phillips, Joanna, Ronen, Sabrina
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
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Abstracts
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218631/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou278.7
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