BI-07 HYPERPOLARIZED [1-(13)C] GLUTAMATE: A METABOLIC IMAGING BIOMARKER OF IDH1 MUTATIONAL STATUS IN GLIOMA

Mutations of the isocitrate dehydrogenase 1 (IDH1) gene are among the most prevalent in low-grade glioma and secondary glioblastoma, represent an early pathogenic event and are being considered a promising therapeutic target. Consequently, non-invasive imaging methods are needed to monitor IDH1 stat...

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Bibliographische Detailangaben
Hauptverfasser: Chaumeil, Myriam, Larson, Peder, Woods, Sarah, Cai, Larry, Eriksson, Pia, Robinson, Aaron, Lupo, Janine, Vigneron, Daniel, Nelson, Sarah, Pieper, Russell, Phillips, Joanna, Ronen, Sabrina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217906/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou239.7
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