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SC-09 TARGETING GLIOBLASTOMA STEM CELLS VIA INHIBITION OF PI3K/AKT PATHWAY ALONE AND IN COMBINATION WITH AUTOPHAGY BLOCKADE
BACKGROUND: Glioblastoma Multiforme (GBM) is the most aggressive form of malignant primary brain tumor. A subset of glioblastoma cells, known as glioblastoma stem-like cells (GSCs), are chemotherapy and radiotherapy-resistent and are hypothesized to be responsible for tumor formation, maintenance, a...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218604/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou275.9 |
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