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Epigenetic pathways and glioblastoma treatment

Glioblastoma multiforme (GBM) is the most common malignant adult brain tumor. Standard GBM treatment includes maximal safe surgical resection with combination radiotherapy and adjuvant temozolomide (TMZ) chemotherapy. Alarmingly, patient survival at five-years is below 10%. This is in part due to th...

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Detalhes bibliográficos
Main Authors: Clarke, Jennifer, Penas, Clara, Pastori, Chiara, Komotar, Ricardo J, Bregy, Amade, Shah, Ashish H, Wahlestedt, Claes, Ayad, Nagi G
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883781/
https://ncbi.nlm.nih.gov/pubmed/23807265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.25440
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