SC-07 CYCLIC INTRANASAL APPLICATION OF NEURAL STEM CELL-MEDIATED ENZYM/PRODRUG THERAPY USING A NOVEL HSV-THYMIDINE KINASE VARIANT INHIBITS INTRACEREBRAL GLIOMA GROWTH AND IMPROVES SURVIVAL

We have recently introduced the concept of intranasal application of NSCs as a noninvasive and direct alternative delivery method for glioma-targeting NSCs. Here, we demonstrate that the repeated non-invasive intranasal administration of tumor-targeting NSC is able to deliver a suicide gene (TK.007)...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Dührsen, Lasse, Reitz, Matthias, Henze, Marvin, Sedlacik, Jan, Riecken, Kristoffer, Fehse, Boris, Westphal, Manfred, Schmidt, Nils Ole
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218602/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou275.7
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