SC-04 NON-UNIFORM NOTCH SIGNALING UNDERLIES HETEROGENEITY WITHIN THE GLIOBLASTOMA STEM CELL POPULATION

Glioblastoma stem cells (GSCs) have the ability to self-renew, differentiate into tumor lineages, and give rise to tumors in immunodeficient animal models. More importantly, GSCs are resistant to current therapies, leading to tumor recurrence. Glioblastoma (GBM) is highly heterogeneous at the molecu...

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Bibliografiset tiedot
Julkaisussa:Neuro Oncol
Päätekijät: Sumru Bayin, N., Si, Sheng, Modrek, Aram, Song, Hae-Ri, Zagzag, David, Hoang, Dung Minh, Wadghiri, Youssef Z., Dolgalev, Igor, Baysan, Mehmet, Heguy, Adriana, Barcellos-Hoff, Mary Helen, Placantonakis, Dimitris
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2014
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Abstracts
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218599/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou275.4
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