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SC-04 NON-UNIFORM NOTCH SIGNALING UNDERLIES HETEROGENEITY WITHIN THE GLIOBLASTOMA STEM CELL POPULATION
Glioblastoma stem cells (GSCs) have the ability to self-renew, differentiate into tumor lineages, and give rise to tumors in immunodeficient animal models. More importantly, GSCs are resistant to current therapies, leading to tumor recurrence. Glioblastoma (GBM) is highly heterogeneous at the molecu...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218599/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou275.4 |
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