SC-04 NON-UNIFORM NOTCH SIGNALING UNDERLIES HETEROGENEITY WITHIN THE GLIOBLASTOMA STEM CELL POPULATION

Glioblastoma stem cells (GSCs) have the ability to self-renew, differentiate into tumor lineages, and give rise to tumors in immunodeficient animal models. More importantly, GSCs are resistant to current therapies, leading to tumor recurrence. Glioblastoma (GBM) is highly heterogeneous at the molecu...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Sumru Bayin, N., Si, Sheng, Modrek, Aram, Song, Hae-Ri, Zagzag, David, Hoang, Dung Minh, Wadghiri, Youssef Z., Dolgalev, Igor, Baysan, Mehmet, Heguy, Adriana, Barcellos-Hoff, Mary Helen, Placantonakis, Dimitris
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218599/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou275.4
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