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SC-28 NOVEL INHIBITORS ON HEDGEHOG PATHWAY TO PREVENT MEDULLOBLASTOMA RELAPSE

Medulloblastoma (MB) is a highly malignant brain tumor affecting predominantly children. MB arises from cerebella stem cells that do not respond to cellular cues to stop dividing, resulting in them becoming Cancer Stem Cells (CSC). These CSCs are resistant to most conventional chemotherapies, and th...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Rodriguez-Blanco, Jezabel, Bin, Li, Martin, Vanesa, Lee, Ethan, Rodriguez, Carmen, Capobianco, Anthony, Robbins, David J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218588/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou275.28
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