PL-03 FEASIBILITY OF GENOMICS-ENABLED THERAPY FOR PEDIATRIC HIGH-GRADE GLIOMAS AND DIFFUSE PONTINE GLIOMAS

Children with pediatric high-grade gliomas (pHGG) including diffuse intrinsic pontine gliomas (DIPG) continue to have a dismal prognosis and, as a result, novel therapeutic approaches are needed. We evaluated whether genomic profiling, defined as sequencing of tumor and germline exomes and tumor RNA...

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Hlavní autoři: Mueller, Sabine, Liang, Winnie, Byron, Sara, Nazemi, Kellie, Leary, Sarah, Kilburn, Lindsay, Prados, Michael, Gupta, Nalin, Craig, David, Carpten, John, Berens, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218469/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou267.3
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