ET-50 LEVETIRACETAM DOWNREGULATES O6-METHYLGUANINE DNA METHYLTRANSFERASE EXPRESSION AND SENSITIZES TEMOZOLOMIDE-RESISTANT GLIOMA CELLS

Temozolomide (TMZ) has become a key agent in treating malignant glioma; nevertheless, its survival benefit remains dismal prognosis. Histone deacetylases are often overexpressed in cancer cells, and this leads to altered expression and activity of numerous proteins involved in carcinogenesis. Recent...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Saito, Norihiko, Aoki, Kazuya, Hirai, Nozomi, Ishii, Masashi, Tani, Mariko, Sato, Kenichiro, Nakayama, Haruo, Harashina, Junichi, Izukura, Hideaki, Ito, Keisuke, Sakurai, Takatoshi, Iwabuchi, Satoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Abstracts
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218145/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou255.47
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky