ET-50 LEVETIRACETAM DOWNREGULATES O6-METHYLGUANINE DNA METHYLTRANSFERASE EXPRESSION AND SENSITIZES TEMOZOLOMIDE-RESISTANT GLIOMA CELLS

Temozolomide (TMZ) has become a key agent in treating malignant glioma; nevertheless, its survival benefit remains dismal prognosis. Histone deacetylases are often overexpressed in cancer cells, and this leads to altered expression and activity of numerous proteins involved in carcinogenesis. Recent...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Saito, Norihiko, Aoki, Kazuya, Hirai, Nozomi, Ishii, Masashi, Tani, Mariko, Sato, Kenichiro, Nakayama, Haruo, Harashina, Junichi, Izukura, Hideaki, Ito, Keisuke, Sakurai, Takatoshi, Iwabuchi, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218145/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou255.47
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados