ET-13 RETROVIRAL REPLICATING VECTOR (RRV)-MEDIATED PRODRUG ACTIVATOR GENE THERAPY WITH CODON-OPTIMIZED NITROREDUCTASE IN EXPERIMENTAL GLIOMA

Our studies to date have demonstrated dramatic survival benefit when tumor-selective retroviral replicating vectors (RRV) are employed for prodrug activator gene therapy in a variety of preclinical cancer models. RRV-mediated gene therapy using yeast cytosine deaminase (CD) is under investigation in...

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Main Authors: Collins, Sara, Logg, Christopher, Inagaki, Akihito, Kamijima, Shuichi, Lehouritis, Panos, Searle, Peter, Tangney, Mark, Kasahara, Noriyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218108/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou255.13
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