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DD-01 LIGAND- AND STRUCTURE-BASED VIRTUAL SCREENING TO DISCOVER POLYPHARMACOLOGICAL DUAL EGFR AND BRD4 INHIBITORS
Combination therapy is the standard-of-care for many cancer patients. The standard treatment for Glioblastoma Multiforme (GBM) includes surgical resection, followed by radiotherapy, and temozolomide (TMZ) subministration. However, resistance to TMZ is nearly universal and tumor recurrence is inevita...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218031/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou246.1 |
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