DD-01 LIGAND- AND STRUCTURE-BASED VIRTUAL SCREENING TO DISCOVER POLYPHARMACOLOGICAL DUAL EGFR AND BRD4 INHIBITORS

Combination therapy is the standard-of-care for many cancer patients. The standard treatment for Glioblastoma Multiforme (GBM) includes surgical resection, followed by radiotherapy, and temozolomide (TMZ) subministration. However, resistance to TMZ is nearly universal and tumor recurrence is inevita...

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Detaylı Bibliyografya
Asıl Yazarlar: Allen, Bryce, Mehta, Saurabh, Ayad, Nagi, Schürer, Stephan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2014
Konular:
Abstracts
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218031/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou246.1
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