CS-08 SONIC HEDGEHOG SIGNALING PROTECTS ATOH1 FROM DEGRADATION MEDIATED BY THE HECT DOMAIN E3 UBIQUITIN LIGASE HUWE1 IN CEREBELLAR GRANULE NEURON PROGENITORS

Cerebellar development requires a balance between several biological processes including proliferation, differentiation and migration. The pro-neural basic helix-loop-helix transcription factor Atoh1 was shown to be a key player controlling the formation of granule neuron progenitors (GNPs). Its unc...

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Bibliografiska uppgifter
Huvudupphovsmän: Forget, Antoine, Bihannic, Laure, Cigna, Sara, Lefevre, Coralie, Remke, Marc, Barnat, Monia, Dodier, Sophie, Shirvani, Hamasseh, Mercier, Audrey, Mensah, Aurore, Garcia, Mickael, Humbert, Sandrine, Taylor, Michael D., Lasorella, Anna, Ayrault, Olivier
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
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Abstracts
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218001/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou242.8
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