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CS-08 SONIC HEDGEHOG SIGNALING PROTECTS ATOH1 FROM DEGRADATION MEDIATED BY THE HECT DOMAIN E3 UBIQUITIN LIGASE HUWE1 IN CEREBELLAR GRANULE NEURON PROGENITORS
Cerebellar development requires a balance between several biological processes including proliferation, differentiation and migration. The pro-neural basic helix-loop-helix transcription factor Atoh1 was shown to be a key player controlling the formation of granule neuron progenitors (GNPs). Its unc...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218001/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou242.8 |
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