CS-01 THE PHOSPHORYLATION OF ATOH1 LEADS TO ITS DEGRADATION MEDIATED BY THE E3 UBIQUITIN LIGASE HUWE1 IN GRANULE NEURON PROGENITORS

Medulloblastoma is the most common malignant pediatric brain tumor and is divided in four subgroups by gene profiling. The well-known subgroup harboring an activation of the Sonic Hedgehog (SHH)/Patched (PTCH) pathway shows an upregulation of the pro-neural basic helix-loop-helix transcription facto...

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Main Authors: Bihannic, Laure, Forget, Antoine, Cigna, Sara Maria, Lefevre, Coralie, Remke, Marc, Barnat, Monia, Dodier, Sophie, Shirvani, Hamasseh, Mercier, Audrey, Mensah, Aurore, Garcia, Mickael, Humbert, Sandrine, Taylor, Michael D., Lasorella, Anna, Ayrault, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217965/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou242.1
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