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CS-26 FIBULIN-3 REGULATES CANONICAL NFkB SIGNALING IN GLIOMA CELLS AND SURROUNDING STROMAL CELLS TO PROMOTE TUMOR INVASION
Fibulin-3 (also known as EFEMP1) is an extracellular matrix protein secreted by glioma cells but absent from normal brain, which increases tumor invasion and resistance to apoptosis. Fibulin-3 activates the Notch pathway in glioma but its downstream mechanisms are unknown. Here we show that fibulin-...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4217983/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou242.26 |
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