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CS-02 SHP2 PROMOTES TUMOR PROGRESSION IN GBM VIA RAS ACTIVATION

Mutations in Ras GTPase and various other components of the Ras signaling pathways are among the most common genetic alterations in human cancers and have also been identified in several familial/developmental syndromes. Ras is also an important factor in many cancers where it is not mutated but fun...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bunda, Severa, Heir, Pardeep, Burrell, Kelly, Ohh, Michael, Zadeh, Gelareh
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217976/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou242.2
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