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CSIG-23. CIC PROTEIN INSTABILITY DRIVES CANCER PHENOTYPES IN GLIOBLASTOMA
The aggressive nature of glioblastoma (GBM) has been attributed to hyperactivation of receptor tyrosine kinases (RTK) and their downstream signaling pathways including Ras/ERK. Pharmacological agents directed against membrane bound RTKs and cytoplasmic kinases within the Ras/ERK signaling pathway ha...
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| Veröffentlicht in: | Neuro Oncol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692980/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.217 |
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