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BI-06 ATRX LOSS IN CHINESE ADULT DIFFUSE ASTROCYTOMAS CORRELATES WITH IDH1 AND TP53 MUTATION AND PREDICTS BETTER OUTCOME IN TP53 MUTATED PATIENTS
The mutation or loss of the ATRX gene was documented in World Health Organization grade 2 to 4 astrocytic tumors and might indicate better prognosis in anaplastic astrocytomas. Astrocytomas with mutation/loss of ATRX also frequently had mutations in IDH1 and TP53. However, the relationships among AT...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4217905/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou239.6 |
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