High Frequency of TP53 Mutations in Juvenile Pilocytic Astrocytomas Indicates Role of TP53 in the Development of These Tumors

In adults, the TP53 tumor suppressor gene is frequently mutated in astrocytic brain tumors which is supposed to represent an early event in their development. In juvenile pilocytic and low‐grade astrocytomas, however, TP53 mutations have until now been reported as rare, which has led to the suggesti...

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Podrobná bibliografie
Vydáno v:Brain Pathol
Hlavní autoři: Hayes, Vanessa M., Dirven, Clemens M.F., Dam, Anke, Verlind, Edwin, Molenaar, Willemina M., Mooij, Jan Jakob A., Hofstra, Robert M.W., Buys, Charles H.C.M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2006
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098180/
https://ncbi.nlm.nih.gov/pubmed/10416986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.1999.tb00535.x
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